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- Avoid drinking alcohol while taking promethazine. Alcohol increases the risks of side effects.
- To help you sleep, you’ll usually take promethazine 20 minutes before you go to bed. It normally takes about 30 minutes to work.
- For preventing travel sickness, you can usually take promethazine the night before a long journey or 1 to 2 hours before a short journey.
- Common side effects include feeling sleepy, headaches, nightmares, and feeling dizzy, restless or confused.
- Promethazine is known by the brand names Avomine, Phenergan, and Sominex.
- When promethazine is mixed with other medicines, it’s also known by the brand names Day & Night Nurse, Fedril, and Night Nurse.
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